Mouse Ikbke Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Ikbke antibody detected the Ikbke protein (arrow).
Ikbke; Ikke; Ikki; Inhibitor of nuclear factor kappa-B kinase subunit epsilon; Inducible I kappa-B kinase
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
Ikke Ikki
Alternative Names
Ikbke Ikke Ikki Inhibitor of nuclear factor kappa-B kinase subunit epsilon Inducible I kappa-B kinase
Molecular Weight(MW)
80953 Da
Function
Phosphorylates inhibitors of NF-kappa-B thus leading to the dissociation of the inhibitor/NF-kappa-B complex and ultimately the degradation of the inhibitor. May play a special role in the immune response. Protects cells against DNA damage- induced cell death (By similarity)
Tissue Specificity
This Mouse Ikbke antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 469-498 amino acids from the Central region of Mouse Ikbke.
Cellular Localization
Cytoplasm (By similarity). Nucleus (By similarity). Nucleus, PML body (By similarity). Note=Targeting to PML nuclear bodies upon DNA damage is TOPORS-dependent (By similarity)
Mouse Ikbke Antibody (Center) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Ikbke antibody detected the Ikbke protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.