Application
Mouse Ksr1 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Ksr1 antibody detected the Ksr1 protein (arrow).| Product Name | Ksr1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Ksr1; Ksr; Kinase suppressor of Ras 1; Protein Hb |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Ksr |
|---|---|
| Alternative Names | Ksr1 Ksr Kinase suppressor of Ras 1 Protein Hb |
| Molecular Weight(MW) | 96755 Da |
| Function | Location-regulated scaffolding protein connecting MEK to RAF. Promotes MEK and RAF phosphorylation and activity through assembly of an activated signaling complex. By itself, it has no demonstrated kinase activity |
| Tissue Specificity | Expressed in brain, spleen and testis. Isoform 1 is highly expressed spleen and weakly in testis, and isoform 2 is highly expressed in brain and weakly in testis |
| Cellular Localization | Cytoplasm. Membrane; Peripheral membrane protein. Endoplasmic reticulum membrane (By similarity). Note=In unstimulated cells, where the phosphorylated form is bound to a 14-3-3 protein, sequestration in the cytoplasm occurs. Following growth factor treatment, the protein is free for membrane translocation, and it moves from the cytoplasm to the cell periphery |
| Entrez Gene | 16706 |
|---|---|
| Nucleotide Accession | NP_038599.1 |
Application
Mouse Ksr1 Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Ksr1 antibody detected the Ksr1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
