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Ksr2 Antibody (C-term)

Catalog Number:OM214222
OM214222
Discount Price
OM214222-100ul
1~2 Week
100ul
OM214222-50ul
50ul
OM214222-20ul
20ul
1~2 Week
Product Profile
Product Name Ksr2 Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias Ksr2; Kinase suppressor of Ras 2
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WB
WB:1:100~500
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names Ksr2
Kinase suppressor of Ras 2
Molecular Weight(MW) 108572 Da
Function Location-regulated scaffold connecting MEK to RAF. Blocks MAP3K8 kinase activity and MAP3K8-mediated signaling. Acts as a negative regulator of MAP3K3-mediated activation of ERK, JNK and NF-kappa-B pathways, inhibiting MAP3K3-mediated interleukin-8 production (By similarity)
Tissue Specificity This Mouse Ksr2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 807-836 amino acids from the C-terminal region of Mouse Ksr2.
Cellular Localization Cytoplasm (By similarity). Membrane; Peripheral membrane protein (By similarity)
Database Links
Nucleotide Accession NP_001030045.1
Application

Application

Mouse Ksr2 Antibody (C-term) western blot analysis in human normal Uterus tissue lysates (35ug/lane).This demonstrates the Ksr2 antibody detected the Ksr2 protein (arrow).
Application Notes WB:1:100~500
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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