Application
Mouse Ltk Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Ltk antibody detected the Ltk protein (arrow).| Product Name | Ltk Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Ltk; Leukocyte tyrosine kinase receptor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Ltk Leukocyte tyrosine kinase receptor |
|---|---|
| Molecular Weight(MW) | 94471 Da |
| Function | Orphan receptor with a tyrosine-protein kinase activity. The exact function of this protein is not known. Studies with chimeric proteins (replacing its extracellular region with that of several known growth factor receptors, such as EGFR and CSFIR) demonstrate its ability to promote growth and specifically neurite outgrowth, and cell survival. Signaling appears to involve the PI3 kinase pathway. Involved in regulation of the secretory pathway involving endoplasmic reticulum (ER) export sites (ERESs) and ER to Golgi transport (By similarity) |
| Tissue Specificity | Subsets of lymphoid and neuronal cells. |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein Isoform B: Endoplasmic reticulum. Note=Retained in the endoplasmic reticulum |
| Entrez Gene | 17005 |
|---|---|
| Nucleotide Accession | NP_976220.2 NP_996825.2 NP_996824.1 |
Application
Mouse Ltk Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Ltk antibody detected the Ltk protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
