Application
Mouse Map3k8 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Map3k8 antibody detected the Map3k8 protein (arrow).Application
Mouse Map3k8 Antibody (N-term) (AP14263a)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse mammary gland followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Map3k8 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | Map3k8 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Map3k8; Cot; Mitogen-activated protein kinase kinase kinase 8; Cancer Osaka thyroid oncogene; Proto-oncogene c-Cot; Serine/threonine-protein kinase cot |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Cot |
|---|---|
| Alternative Names | Map3k8 Cot Mitogen-activated protein kinase kinase kinase 8 Cancer Osaka thyroid oncogene Proto-oncogene c-Cot Serine/threonine-protein kinase cot |
| Molecular Weight(MW) | 52942 Da |
| Function | Required for TLR4 activation of the MEK/ERK pathway. Able to activate NF-kappa-B 1 by stimulating proteasome-mediated proteolysis of NF-kappa-B 1/p105. Plays a role in the cell cycle (By similarity) |
| Tissue Specificity | High in adult submandibular gland, thymus, spleen and newborn digestive tract |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 26410 |
|---|---|
| Nucleotide Accession | NP_031772.1 |
Application
Mouse Map3k8 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Map3k8 antibody detected the Map3k8 protein (arrow).
Application
Mouse Map3k8 Antibody (N-term) (AP14263a)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse mammary gland followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Map3k8 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
