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Map3k9 Antibody (C-term)

Catalog Number:OM214253
OM214253
Discount Price
OM214253-100ul
1~2 Week
100ul
OM214253-50ul
50ul
OM214253-20ul
20ul
1~2 Week
Product Profile
Product Name Map3k9 Antibody (C-term)
Antibody Type Primary Antibodies
Antigen Alias Map3k9; Mitogen-activated protein kinase kinase kinase 9
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names Map3k9
Mitogen-activated protein kinase kinase kinase 9
Molecular Weight(MW) 118805 Da
Function Serine/threonine kinase which acts as an essential component of the MAP kinase signal transduction pathway. Plays an important role in the cascades of cellular responses evoked by changes in the environment. Once activated, acts as an upstream activator of the MKK/JNK signal transduction cascade through the phosphorylation of MAP2K4/MKK4 and MAP2K7/MKK7 which in turn activate the JNKs. The MKK/JNK signaling pathway regulates stress response via activator protein-1 (JUN) and GATA4 transcription factors. Plays also a role in mitochondrial death signaling pathway, including the release cytochrome c, leading to apoptosis (By similarity)
Tissue Specificity Expressed in cochlea and utricle.
Database Links
Entrez Gene 338372
Nucleotide Accession NP_796369.2 NP_001167578.1
Application

Application

Mouse Map3k9 Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the Map3k9 antibody detected the Map3k9 protein (arrow).

Application

Mouse Map3k9 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Map3k9 antibody detected the Map3k9 protein (arrow).

Application

Mouse Map3k9 Antibody (C-term) (AP14135b)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse live tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Map3k9 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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