Application
Mouse Matk Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the Matk antibody detected the Matk protein (arrow).Application
Mouse Matk Antibody (C-term) (AP14271b)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Matk Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | Matk Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Matk; Ctk; Ntk; Megakaryocyte-associated tyrosine-protein kinase; Protein kinase NTK; Tyrosine-protein kinase CTK |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Ctk Ntk |
|---|---|
| Alternative Names | Matk Ctk Ntk Megakaryocyte-associated tyrosine-protein kinase Protein kinase NTK Tyrosine-protein kinase CTK |
| Molecular Weight(MW) | 56056 Da |
| Function | Could play a significant role in the signal transduction of hematopoietic cells. May regulate tyrosine kinase activity of SRC-family members in brain by specifically phosphorylating their C-terminal regulatory tyrosine residue which acts as a negative regulatory site. It may play an inhibitory role in the control of T-cell proliferation |
| Tissue Specificity | Most abundant in brain, and to a lesser extent in the spleen, the thymus and the liver. Also found in the T-cell lineage |
| Cellular Localization | Cytoplasm. Membrane (By similarity). Note=In platelets, 90% of MATK localizes to the membrane fraction, and translocates to the cytoskeleton upon thrombin stimulation (By similarity) |
| Entrez Gene | 17179 |
|---|---|
| Nucleotide Accession | NP_034898.1 |
Application
Mouse Matk Antibody (C-term) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the Matk antibody detected the Matk protein (arrow).
Application
Mouse Matk Antibody (C-term) (AP14271b)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Matk Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
