Application
Mouse Mcm2 Antibody (C-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the Mcm2 antibody detected the Mcm2 protein (arrow).| Product Name | Mcm2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Bm28, Cdcl1, Kiaa0030, Mcmd2 |
|---|---|
| Alternative Names | Mcm2 Bm28 Cdcl1 Kiaa0030 Mcmd2 DNA replication licensing factor MCM2 Minichromosome maintenance protein 2 homolog Nuclear protein BM28 |
| Molecular Weight(MW) | 102078 Da |
| Function | Acts as component of the MCM2-7 complex (MCM complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the MCM2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differentially to the complex helicase activity. Required for the entry in S phase and for cell division |
| Tissue Specificity | This Mouse Mcm2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 711-742 amino acids from the C-terminal region of mouse Mcm2. |
| Cellular Localization | Nucleus (Probable). |
| Entrez Gene | 17216 |
|---|---|
| Nucleotide Accession | NP_032590.2 |
Application
Mouse Mcm2 Antibody (C-term) western blot analysis in mouse Neuro-2a cell line lysates (35ug/lane).This demonstrates the Mcm2 antibody detected the Mcm2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
