Application
Mouse Mylk3 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Mylk3 antibody detected the Mylk3 protein (arrow).| Product Name | Mylk3 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Mylk3 Putative myosin light chain kinase 3 |
|---|---|
| Molecular Weight(MW) | 86372 Da |
| Function | Kinase that phosphorylates MYL2 in vitro. Has been proposed to be calmodulin-dependent (PubMed=17885681), although MYL2 phosphorylation has also been observed in the presence or absence of calmodulin (PubMed:18202317). Promotes sarcomere formation in cardiomyocytes and increases cardiomyocyte contractility |
| Tissue Specificity | Restricted to cardiomyocytes (at protein level). Down-regulated in heart after experimental myocardial infarction at the protein level; no significant changes at the mRNA level |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 213435 |
|---|---|
| Nucleotide Accession | NP_780650.2 |
Application
Mouse Mylk3 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Mylk3 antibody detected the Mylk3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
