Application
Mouse Nek11 Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Nek11 antibody detected the Nek11 protein (arrow).Application
Mouse Nek11 Antibody (N-term) (AP14448a)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Nek11 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | Nek11 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Nek11; Serine/threonine-protein kinase Nek11; Never in mitosis A-related kinase 11 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Nek11 Serine/threonine-protein kinase Nek11 Never in mitosis A-related kinase 11 |
|---|---|
| Molecular Weight(MW) | 71648 Da |
| Function | Protein kinase which plays an important role in the G2/M checkpoint response to DNA damage. Controls degradation of CDC25A by directly phosphorylating it on residues whose phosphorylation is required for BTRC-mediated polyubiquitination and degradation (By similarity) |
| Tissue Specificity | This Mouse Nek11 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 98-126 amino acids from the N-terminal region of Mouse Nek11. |
| Cellular Localization | Nucleus (By similarity). Nucleus, nucleolus (By similarity). Note=Nuclear during interphase but moves to the polar microtubules during prometaphase and metaphase. Accumulates in the nucleolus in G1/S-arrested cells (By similarity) |
| Entrez Gene | 208583 |
|---|---|
| Nucleotide Accession | NP_766049.2 |
Application
Mouse Nek11 Antibody (N-term) western blot analysis in mouse kidney tissue lysates (35ug/lane).This demonstrates the Nek11 antibody detected the Nek11 protein (arrow).
Application
Mouse Nek11 Antibody (N-term) (AP14448a)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Nek11 Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
