Application
Western blot analysis of mouse MOGT2 Antibody (C-term) (Cat# AP1122b) in HL60 cell line lysates (35ug/lane). MOGT2 (arrow) was detected using the purified Pab (1:60 dilution).| Product Name | MOGT2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Mogat2; Dgat2l5; Mgat1l; 2-acylglycerol O-acyltransferase 2; Acyl-CoA:monoacylglycerol acyltransferase 2; Diacylglycerol acyltransferase 2-like protein 5; Monoacylglycerol O-acyltransferase 1-like; Monoacylglycerol O-acyltransferase 2 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:50~100 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Dgat2l5 Mgat1l |
|---|---|
| Alternative Names | Mogat2 Dgat2l5 Mgat1l 2-acylglycerol O-acyltransferase 2 Acyl-CoA:monoacylglycerol acyltransferase 2 Diacylglycerol acyltransferase 2-like protein 5 Monoacylglycerol O-acyltransferase 1-like Monoacylglycerol O-acyltransferase 2 |
| Molecular Weight(MW) | 38591 Da |
| Function | Catalyzes the formation of diacylglycerol from 2- monoacylglycerol and fatty acyl-CoA. Has a preference toward monoacylglycerols containing unsaturated fatty acids in an order of C18:3 > C18:2 > C18:1 > C18:0. Plays a central role in absorption of dietary fat in the small intestine by catalyzing the resynthesis of triacylglycerol in enterocytes. May play a role in diet-induced obesity |
| Tissue Specificity | Mainly expressed in small intestine. Detected in the small intestine in a proximal-to-distal gradient that correlated with fat absorption pattern. Present not only in the villi, but also in the crypt regions of the small intestine, which suggests that expression occurs prior to the maturation of enterocytes. Not detectable in other sections of the digestive tract, including stomach, cecum, colon and rectum, or other tissues such as kidney, liver and adipocytes (at protein level) Also detected in kidney, adipose and stomach. Expressed at very low level in liver, skeletal muscle and spleen. Not expressed in brain, heart, lung, skin, testis and thymus |
| Cellular Localization | Endoplasmic reticulum membrane; Multi-pass membrane protein |
| Entrez Gene | 233549 |
|---|
Application
Western blot analysis of mouse MOGT2 Antibody (C-term) (Cat# AP1122b) in HL60 cell line lysates (35ug/lane). MOGT2 (arrow) was detected using the purified Pab (1:60 dilution).| Application Notes | WB:1:50~100 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
