Application
Mouse Nod1 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the Nod1 antibody detected the Nod1 protein (arrow).| Product Name | Nod1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Nod1; Card4; Nucleotide-binding oligomerization domain-containing protein 1; Caspase recruitment domain-containing protein 4 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Card4 |
|---|---|
| Alternative Names | Nod1 Card4 Nucleotide-binding oligomerization domain-containing protein 1 Caspase recruitment domain-containing protein 4 |
| Molecular Weight(MW) | 107740 Da |
| Function | Enhances caspase-9-mediated apoptosis. Induces NF-kappa- B activity via RIPK2 and IKK-gamma. Confers responsiveness to intracellular bacterial lipopolysaccharides (LPS). Forms an intracellular sensing system along with ARHGEF2 for the detection of microbial effectors during cell invasion by pathogens. Recruits NLRP10 to the cell membrane following bacterial infection (By similarity) |
| Tissue Specificity | This Mouse Nod1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 555-584 amino acids from the Central region of mouse Nod1. |
| Cellular Localization | Cytoplasm (By similarity). Cell membrane (By similarity). Apical cell membrane (By similarity). Basolateral cell membrane (By similarity). Note=Detected in the cytoplasm and at the cell membrane. Following bacterial infection, localizes to bacterial entry sites in the cell membrane. Recruited to the basolateral and apical membranes in polarized epithelial cells (By similarity) |
| Entrez Gene | 107607 |
|---|---|
| Nucleotide Accession | NP_001164478.1 |
Application
Mouse Nod1 Antibody (Center) western blot analysis in mouse spleen tissue lysates (35ug/lane).This demonstrates the Nod1 antibody detected the Nod1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
