Application
Mouse Pdk3 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Pdk3 antibody detected the Pdk3 protein (arrow).Application
Mouse Pdk3 Antibody (C-term) (AP14274b)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Pdk3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | Pdk3 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Pdk3 [Pyruvate dehydrogenase [lipoamide]] kinase isozyme 3 mitochondrial Pyruvate dehydrogenase kinase isoform 3 |
|---|---|
| Molecular Weight(MW) | 47923 Da |
| Function | Inhibits pyruvate dehydrogenase activity by phosphorylation of the E1 subunit PDHA1, and thereby regulates glucose metabolism and aerobic respiration. Can also phosphorylate PDHA2. Decreases glucose utilization and increases fat metabolism in response to prolonged fasting, and as adaptation to a high-fat diet. Plays a role in glucose homeostasis and in maintaining normal blood glucose levels in function of nutrient levels and under starvation. Plays a role in the generation of reactive oxygen species (By similarity) |
| Tissue Specificity | This Mouse Pdk3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 386-414 amino acids from the C-terminal region of Mouse Pdk3. |
| Cellular Localization | Mitochondrion matrix (By similarity). |
| Entrez Gene | 236900 |
|---|---|
| Nucleotide Accession | NP_663605.1 |
Application
Mouse Pdk3 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Pdk3 antibody detected the Pdk3 protein (arrow).
Application
Mouse Pdk3 Antibody (C-term) (AP14274b)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Pdk3 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
