Application
Mouse PINK Antibody (Center) western blot analysis in 293,MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PINK antibody detected the PINK protein (arrow).| Product Name | PINK Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Pink1 Serine/threonine-protein kinase PINK1 mitochondrial BRPK PTEN-induced putative kinase protein 1 |
|---|---|
| Molecular Weight(MW) | 63181 Da |
| Function | Protects against mitochondrial dysfunction during cellular stress, potentially by phosphorylating mitochondrial proteins (By similarity). Involved in the clearance of damaged mitochondria via selective autophagy (mitophagy) (By similarity) It is necessary for PARK2 recruitment to dysfunctional mitochondria to initiate their degradation (By similarity) |
| Tissue Specificity | High levels expressed in testis, lower levels in brain, heart, lung, liver and kidney |
| Cellular Localization | Mitochondrion outer membrane; Single-pass membrane protein (By similarity). Cytoplasm, cytosol (By similarity) |
| Entrez Gene | 68943 |
|---|---|
| Nucleotide Accession | NP_081156.2 |
Application
Mouse PINK Antibody (Center) western blot analysis in 293,MDA-MB231 cell line lysates (35ug/lane).This demonstrates the PINK antibody detected the PINK protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
