Application
Mouse Pkdcc Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Pkdcc antibody detected the Pkdcc protein (arrow).Application
Mouse Pkdcc Antibody (N-term) (AP14694a)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse live tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Pkdcc Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | Pkdcc Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Sgk493, Vlk |
|---|---|
| Alternative Names | Pkdcc Sgk493 Vlk Protein kinase domain-containing protein cytoplasmic Protein kinase-like protein SgK493 Sugen kinase 493 Vertebrate lonesome kinase |
| Molecular Weight(MW) | 53841 Da |
| Function | Protein kinase which is required for longitudinal bone growth through regulation of chondrocyte differentiation. Involved in protein transport from the Golgi apparatus to the plasma membrane |
| Tissue Specificity | Strongly expressed in adult heart, liver and testis with weak expression in brain, spleen, lung and thymus. In the humerus, strongly expressed in early flat proliferative chondrocytes. In the embryo, expressed in the anterior visceral endoderm and anterior primitive streak at E6.5. At E7.5, expressed in the anterior definitive endoderm (ADE) and anterior mesoderm but not in the notochord. At E8.0, expressed in the ADE and anterior embryonic mesoderm. At E8.5, expressed more broadly in anterior tissues and at the midline of the neural plate in the midbrain region as well as the lateral margins of the neural plate posterior to the metencephalic region. Also weakly expressed in the anterior mesenchyme. At E9.5, strongest expression in branchial arches and limb buds. During mid-gestation, expression continues in mesenchymal cells, particularly in areas where these cells condense |
| Cellular Localization | Golgi apparatus. |
| Entrez Gene | 106522 |
|---|---|
| Nucleotide Accession | XP_001480532.1 NP_598878.2 |
Application
Mouse Pkdcc Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Pkdcc antibody detected the Pkdcc protein (arrow).
Application
Mouse Pkdcc Antibody (N-term) (AP14694a)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse live tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Pkdcc Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
