Application
Mouse Prkx Antibody (N-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the Prkx antibody detected the Prkx protein (arrow).| Product Name | Prkx Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Pkare |
|---|---|
| Alternative Names | Prkx Pkare cAMP-dependent protein kinase catalytic subunit PRKX PKA-related protein kinase |
| Molecular Weight(MW) | 40467 Da |
| Function | Serine/threonine protein kinase regulated by and mediating cAMP signaling in cells. Acts through phosphorylation of downstream targets that may include CREB, SMAD6 and PKD1 and has multiple functions in cellular differentiation and epithelial morphogenesis. Regulates myeloid cell differentiation through SMAD6 phosphorylation. Involved in nephrogenesis by stimulating renal epithelial cell migration and tubulogenesis. Also involved in angiogenesis through stimulation of endothelial cell proliferation, migration and vascular-like structure formation |
| Tissue Specificity | Widely expressed. |
| Cellular Localization | Cytoplasm (By similarity). Nucleus (By similarity). Note=cAMP induces nuclear translocation (By similarity) |
| Entrez Gene | 19108 |
|---|---|
| Nucleotide Accession | NP_058675.1 |
Application
Mouse Prkx Antibody (N-term) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the Prkx antibody detected the Prkx protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
