Application
Mouse Pskh1 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Pskh1 antibody detected the Pskh1 protein (arrow).Application
Mouse Pskh1 Antibody (C-term) (AP14701b)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Pskh1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | Pskh1 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Pskh1 Serine/threonine-protein kinase H1 Protein serine kinase H1 |
|---|---|
| Molecular Weight(MW) | 48095 Da |
| Function | May be a SFC-associated serine kinase (splicing factor compartment-associated serine kinase) with a role in intranuclear SR protein (non-snRNP splicing factors containing a serine/arginine-rich domain) trafficking and pre-mRNA processing (By similarity) |
| Tissue Specificity | This Mouse Pskh1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 278-307 amino acids from the C-terminal region of Mouse Pskh1. |
| Cellular Localization | Golgi apparatus (By similarity). Cytoplasm, cytoskeleton, centrosome (By similarity). Nucleus speckle (By similarity). Endoplasmic reticulum membrane; Lipid-anchor (By similarity). Cell membrane; Lipid-anchor (By similarity) Cytoplasm (By similarity). Note=Localized in the brefeldin A- sensitive Golgi compartment, at centrosomes, in the nucleus with a somewhat speckle-like presence, membrane-associated to the endoplasmic reticulum (ER) and the plasma membrane (PM), and more diffusely in the cytoplasm. Found to concentrate in splicing factor compartments (SFCs) within the nucleus of interphase cells The acylation-negative form may be only cytoplasmic and nuclear Acylation seems to allow the sequestering to the intracellular membranes. Myristoylation may mediate targeting to the intracellular non-Golgi membranes and palmitoylation may mediate the targeting to the Golgi membranes. Dual acylation is required to stabilize the interaction with Golgi membranes (By similarity) |
| Entrez Gene | 244631 |
|---|---|
| Nucleotide Accession | NP_775608.1 |
Application
Mouse Pskh1 Antibody (C-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the Pskh1 antibody detected the Pskh1 protein (arrow).
Application
Mouse Pskh1 Antibody (C-term) (AP14701b)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Pskh1 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
