Application
Mouse Pxk Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the Pxk antibody detected the Pxk protein (arrow).Application
Western blot analysis of Pxk (arrow) using rabbit polyclonal Mouse Pxk Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Pxk gene.Application
Mouse Pxk Antibody (Center) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Pxk antibody detected the Pxk protein (arrow).Application
Mouse Pxk Antibody (Center) (AP14159c)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Pxk Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | Pxk Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Pxk PX domain-containing protein kinase-like protein Modulator of Na K-ATPase |
|---|---|
| Molecular Weight(MW) | 65231 Da |
| Function | Binds to and modulates brain Na,K-ATPase subunits ATP1B1 and ATP1B3 and may thereby participate in the regulation of electrical excitability and synaptic transmission. May not display kinase activity |
| Tissue Specificity | Isoform 1 is present in all tissues examined. Isoform 2 is found in all tissues except skeletal muscle and very low levels in spleen. Both isoforms are widely expressed throughout the nervous system however levels of isoform 2 are higher in purified hippocampal and cortical neurons whereas glial cells express more isoform 1 than isoform 2 |
| Cellular Localization | Cytoplasm. Cell membrane; Peripheral membrane protein. Note=Also associates with the plasma membrane |
| Entrez Gene | 218699 |
|---|---|
| Nucleotide Accession | NP_663433.2 NP_840063.1 |
Application
Mouse Pxk Antibody (Center) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the Pxk antibody detected the Pxk protein (arrow).
Application
Western blot analysis of Pxk (arrow) using rabbit polyclonal Mouse Pxk Antibody (Center) . 293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected (Lane 2) with the Pxk gene.
Application
Mouse Pxk Antibody (Center) western blot analysis in mouse brain tissue lysates (35ug/lane).This demonstrates the Pxk antibody detected the Pxk protein (arrow).
Application
Mouse Pxk Antibody (Center) (AP14159c)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Pxk Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
