Application
Mouse Sik2 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Sik2 antibody detected the Sik2 protein (arrow).| Product Name | Sik2 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Snf1lk2 |
|---|---|
| Alternative Names | Sik2 Snf1lk2 Serine/threonine-protein kinase SIK2 Salt-inducible kinase 2 Serine/threonine-protein kinase SNF1-like kinase 2 |
| Molecular Weight(MW) | 104198 Da |
| Function | Phosphorylates 'Ser-789' of IRS1 in insulin-stimulated adipocytes, potentially modulating the efficiency of insulin signal transduction. Inhibits CREB activity by phosphorylating and repressing TORCs, the CREB-specific coactivators |
| Tissue Specificity | Present in both white and brown adipose tissues with levels increasing during adipocyte differentiation Lower levels observed in the testis |
| Cellular Localization | Cytoplasm. |
| Entrez Gene | 235344 |
|---|---|
| Nucleotide Accession | NP_848825.2 |
Application
Mouse Sik2 Antibody (Center) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Sik2 antibody detected the Sik2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
