Application
MOUSE Sike1 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the MOUSE Sike1 antibody detected the MOUSE Sike1 protein (arrow).| Product Name | Sike1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | Sike1 Suppressor of IKBKE 1 Suppressor of IKK-epsilon |
|---|---|
| Molecular Weight(MW) | 23522 Da |
| Function | Physiological suppressor of IKK-epsilon and TBK1 that plays an inhibitory role in virus- and TLR3-triggered IRF3 Inhibits TLR3-mediated activation of interferon-stimulated response elements (ISRE) and the IFN-beta promoter. May act by disrupting the interactions of IKBKE or TBK1 with TICAM1/TRIF, IRF3 and DDX58/RIG-I. Does not inhibit NF-kappa-B activation pathways (By similarity) |
| Tissue Specificity | This MOUSE Sike1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 36-63 amino acids from the N-terminal region of mouse Sike1. |
| Cellular Localization | Cytoplasm (By similarity). |
| Entrez Gene | 66641 |
|---|---|
| Nucleotide Accession | NP_079955.1 |
Application
MOUSE Sike1 Antibody (N-term) western blot analysis in mouse liver tissue lysates (35ug/lane).This demonstrates the MOUSE Sike1 antibody detected the MOUSE Sike1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
