Application
Mouse Sin3a Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Sin3a antibody detected the Sin3a protein (arrow).| Product Name | Sin3a Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Kiaa4126 |
|---|---|
| Alternative Names | Sin3a Kiaa4126 Paired amphipathic helix protein Sin3a Histone deacetylase complex subunit Sin3a Transcriptional corepressor Sin3a |
| Molecular Weight(MW) | 145088 Da |
| Function | Acts as a transcriptional repressor. Corepressor for REST. Interacts with MXI1 to repress MYC responsive genes and antagonize MYC oncogenic activities. Also interacts with MXD1-MAX heterodimers to repress transcription by tethering SIN3A to DNA Acts cooperatively with OGT to repress transcription in parallel with histone deacetylation |
| Tissue Specificity | Widely expressed. Highest levels in testis, lung and thymus |
| Cellular Localization | Nucleus. Nucleus, nucleolus. Note=Recruited to the nucleolus by SAP30L (By similarity) |
| Entrez Gene | 20466 |
|---|---|
| Nucleotide Accession | NP_001103820.1 |
Application
Mouse Sin3a Antibody (C-term) western blot analysis in mouse NIH-3T3 cell line lysates (35ug/lane).This demonstrates the Sin3a antibody detected the Sin3a protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
