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TLR6 Antibody (C-term)
Catalog Number:OM214467
OM214467
Discount Price
OM214467-100ul
1~2 Week
100ul
OM214467-50ul
50ul
OM214467-20ul
20ul
1~2 Week
Product Profile
Product Name TLR6 Antibody (C-term)
Antibody Type Primary Antibodies
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Alternative Names Tlr6
Toll-like receptor 6
CD_antigen=CD286
Flags: Precursor
Molecular Weight(MW) 91116 Da
Function Participates in the innate immune response to Gram- positive bacteria and fungi. Specifically recognizes diacylated and, to a lesser extent, triacylated lipopeptides. Acts via MYD88 and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Cooperates with TLR2 for the cellular activation
Tissue Specificity Detected in thymus, spleen, ovary and lung.
Cellular Localization Cell membrane; Single-pass type I membrane protein. Cytoplasmic vesicle, phagosome membrane; Single-pass type I membrane protein
Database Links
Entrez Gene 21899
Application

Application

Western blot analysis of Mouse TLR6 Antibody (C-term) (Cat.# AP1506c) in K562 cell line lysates (35ug/lane). TLR6 (arrow) was detected using the purified Pab.

Application

Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.

Application

Formalin-fixed and paraffin-embedded human lung carcinoma tissue reacted with Mouse TLR6 antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.
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