Application
Mouse Trem2 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Trem2 antibody detected the Trem2 protein (arrow).| Product Name | Trem2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Trem2a, Trem2b, Trem2c |
|---|---|
| Alternative Names | Trem2 Trem2a Trem2b Trem2c Triggering receptor expressed on myeloid cells 2 Triggering receptor expressed on monocytes 2 |
| Molecular Weight(MW) | 24527 Da |
| Function | May have a role in chronic inflammations and may stimulate production of constitutive rather than inflammatory chemokines and cytokines. Forms a receptor signaling complex with TYROBP and triggers activation of the immune responses in macrophages and dendritic cells |
| Tissue Specificity | Expressed at higher levels in the CNS, heart and lung than in lymph nodes or in other non-lymphoid tissues such as kidney, liver and testis. In the CNS not all microglia express TREM2. Brain regions with an incomplete blood-brain barrier had the lowest percentages of TREM2 expressing microglia, whereas the lateral entorhinal and cingulate cortex had the highest percentages |
| Cellular Localization | Isoform 1: Cell membrane; Single-pass type I membrane protein (Potential) |
| Entrez Gene | 83433 |
|---|---|
| Nucleotide Accession | NP_112544.1 |
Application
Mouse Trem2 Antibody (N-term) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the Trem2 antibody detected the Trem2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
