Application
Mouse Tssk2 Antibody (C-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the Tssk2 antibody detected the Tssk2 protein (arrow).Application
Mouse Tssk2 Antibody (C-term) (AP14300b)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Tssk2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | Tssk2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | Stk22b |
|---|---|
| Alternative Names | Tssk2 Stk22b Testis-specific serine/threonine-protein kinase 2 Serine/threonine-protein kinase 22B |
| Molecular Weight(MW) | 41022 Da |
| Function | Testis-specific serine/threonine-protein kinase required during spermatid development. Phosphorylates 'Ser-281' of TSKS and SPAG16. Involved in the late stages of spermatogenesis, during the reconstruction of the cytoplasm. During spermatogenesis, required for the transformation of a ring-shaped structure around the base of the flagellum originating from the chromatoid body |
| Tissue Specificity | Testis-specific. Expressed only in the spermatids postmeiotically at the final stages of cytodifferentiation in the seminiferous tubules (at protein level). Not detected in released sperms in the lumen of the seminiferous tubules. Also present in the epididymal sperm (at protein level) |
| Cellular Localization | Cytoplasm. Cytoplasm, cytoskeleton, centrosome, centriole. Cytoplasmic vesicle, secretory vesicle, acrosome. Note=Present in the cytoplasm of elongating spermatids In spermatozoa, localizes in the equatorial segment, neck, the midpiece and in a specific sperm head compartment. In spermatids, concentrates in centrioles during flagellogenesis. Localizes in the tail and acrosomal regions of epididymal sperm |
| Entrez Gene | 22115 |
|---|
Application
Mouse Tssk2 Antibody (C-term) western blot analysis in mouse testis tissue lysates (35ug/lane).This demonstrates the Tssk2 antibody detected the Tssk2 protein (arrow).
Application
Mouse Tssk2 Antibody (C-term) (AP14300b)immunohistochemistry analysis in formalin fixed and paraffin embedded mouse testis tissue followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of Mouse Tssk2 Antibody (C-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
