Application
MPP8 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MPP8 antibody detected the MPP8 protein (arrow).Application
MPP8 Antibody (N-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | MPP8 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBFC |
| WB:1:100~500 FC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MPP8 |
|---|---|
| Alternative Names | MPHOSPH8 MPP8 M-phase phosphoprotein 8 Two hybrid-associated protein 3 with RanBPM |
| Molecular Weight(MW) | 97182 Da |
| Function | Involved in transcriptional regulation. Specifically recognizes and binds methylated 'Lys-9' of histone H3 (H3K9me) and promotes DNA methylation by recruiting DNMT3A to target CpG sites; these can be situated within the coding region of the gene Mediates down-regulation of CDH1 expression |
| Tissue Specificity | This MPP8 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 203-233 amino acids from the N-terminal region of human MPP8. |
| Cellular Localization | Nucleus. Note=Detected on heterochromatin. Detected on nucleosomes |
| Entrez Gene | 54737 |
|---|---|
| Nucleotide Accession | NP_059990.2 |
Application
MPP8 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MPP8 antibody detected the MPP8 protein (arrow).
Application
MPP8 Antibody (N-term) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 FC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
