Application
MRPL41 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MRPL41 antibody detected the MRPL41 protein (arrow).| Product Name | MRPL41 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BMRP, MRPL27, RPML27 |
|---|---|
| Alternative Names | MRPL41 BMRP MRPL27 RPML27 39S ribosomal protein L41 mitochondrial 39S ribosomal protein L27 homolog Bcl-2-interacting mitochondrial ribosomal protein L41 Cell proliferation-inducing gene 3 protein MRP-L27 homolog |
| Molecular Weight(MW) | 15383 Da |
| Function | Component of the mitochondrial ribosome large subunit. Also involved in apoptosis and cell cycle. Enhances p53/TP53 stability, thereby contributing to p53/TP53-induced apoptosis in response to growth-inhibitory condition. Enhances p53/TP53 translocation to the mitochondria. Has the ability to arrest the cell cycle at the G1 phase, possibly by stabilizing the CDKN1A and CDKN1B (p27Kip1) proteins |
| Tissue Specificity | Present in kidney, liver, thymus and testis, and at lower level in brain and spleen (at protein level) |
| Cellular Localization | Mitochondrion. |
| Entrez Gene | 64975 |
|---|---|
| Nucleotide Accession | NP_115866.1 |
Application
MRPL41 Antibody (N-term) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the MRPL41 antibody detected the MRPL41 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
