Application
Western blot analysis of Msx2 (arrow) using rabbit polyclonal Msx2 Antibody (Human C-term) .293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the Msx2 gene (Lane 2) (Origene Technologies).Application
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Msx2 Antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | Msx2 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | Homeobox protein MSX-2; Hox-8; MSX2; HOX8 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:50~100 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HOX8 |
|---|---|
| Alternative Names | Homeobox protein MSX-2 Hox-8 MSX2 HOX8 |
| Molecular Weight(MW) | 28897 Da |
| Function | Acts as a transcriptional regulator in bone development. Represses the ALPL promoter activity and antogonizes the stimulatory effect of DLX5 on ALPL expression during osteoblast differentiation. Probable morphogenetic role. May play a role in limb-pattern formation. In osteoblasts, suppresses transcription driven by the osteocalcin FGF response element (OCFRE). Binds to the homeodomain-response element of the ALPL promoter |
| Tissue Specificity | This Msx2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human MSX2. |
| Cellular Localization | Nucleus. |
| Entrez Gene | 4488 |
|---|
Application
Western blot analysis of Msx2 (arrow) using rabbit polyclonal Msx2 Antibody (Human C-term) .293 cell lysates (2 ug/lane) either nontransfected (Lane 1) or transiently transfected with the Msx2 gene (Lane 2) (Origene Technologies).
Application
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Msx2 Antibody (C-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:50~100 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
