Application
The anti-MTMR6 C-term Pab is used in Western blot to detect MTMR6 in mouse heart tissue lysate.Application
Formalin-fixed and paraffin-embedded human testis tissue reacted with MTMR6 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | MTMR6 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MTMR6; Myotubularin-related protein 6 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | MTMR6 Myotubularin-related protein 6 |
|---|---|
| Molecular Weight(MW) | 71968 Da |
| Function | Phosphatase that acts on lipids with a phosphoinositol headgroup. Acts as a negative regulator of KCNN4/KCa3.1 channel activity in CD4+ T-cells possibly by decreasing intracellular levels of phosphatidylinositol 3 phosphatase. Negatively regulates proliferation of reactivated CD4+ T-cells |
| Tissue Specificity | Expressed in CD4+ T-cells. |
| Cellular Localization | Nucleus envelope. |
| Entrez Gene | 9107 |
|---|
Application
The anti-MTMR6 C-term Pab is used in Western blot to detect MTMR6 in mouse heart tissue lysate.
Application
Formalin-fixed and paraffin-embedded human testis tissue reacted with MTMR6 antibody (C-term), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
