Application
MURC Antibody (N-term) western blot analysis in mouse spleen tissue lysates (15ug/lane).This demonstrates the MURC antibody detected MURC protein (arrow).Application
MURC Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MURC Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Product Name | MURC Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MURC; Muscle-related coiled-coil protein; Muscle-restricted coiled-coil protein |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Alternative Names | MURC Muscle-related coiled-coil protein Muscle-restricted coiled-coil protein |
|---|---|
| Molecular Weight(MW) | 41899 Da |
| Function | Induces RHOA activation and activates NPPA transcription and myofibrillar organization through the Rho/ROCK signaling pathway |
| Tissue Specificity | This MURC antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 94-124 amino acids from the N-terminal region of human MURC. |
| Cellular Localization | Cytoplasm, myofibril, sarcomere (By similarity). Cytoplasm (By similarity). Note=In cardiomyocytes, accumulates in the Z-line of the sarcomere. In vascular smooth muscle cells, detected diffusely throughout the cytoplasm (By similarity) |
| Entrez Gene | 347273 |
|---|---|
| Nucleotide Accession | NP_001018126.1 |
Application
MURC Antibody (N-term) western blot analysis in mouse spleen tissue lysates (15ug/lane).This demonstrates the MURC antibody detected MURC protein (arrow).
Application
MURC Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human lung carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MURC Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
