mut-7; Probable exonuclease mut-7; Exonuclease 3'-5' domain-containing protein 3 homolog
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:200
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Alternative Names
mut-7 Probable exonuclease mut-7 Exonuclease 3'-5' domain-containing protein 3 homolog
Molecular Weight(MW)
105569 Da
Function
Represses the transposition of Tc1, Tc3, Tc4, and Tc5, perhaps by degrading transposon-specific messages. Also affects sperm development, sensitivity to RNAi of mainly germline expressed genes, silencing of some germline transgenes, X chromosome loss, and is required for cosuppression (functional silencing of chromosomal loci induced by transgenes) and for silencing induced by antisense RNA oligomers
Tissue Specificity
This Mut-7 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of C. elegans Mut-7.
Western blot analysis of anti-mUT-7 Pab in C. Elegans lysate (1:200 dilution). Data courtesy of Dr. John Kim, University of Michigan.
Application Notes
WB:1:200
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS.