Application
MXI1 Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the MXI1 antibody detected the MXI1 protein (arrow).| Product Name | MXI1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MXI1; BHLHC11; Max-interacting protein 1; Class C basic helix-loop-helix protein 11 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BHLHC11 |
|---|---|
| Alternative Names | MXI1 BHLHC11 Max-interacting protein 1 Class C basic helix-loop-helix protein 11 |
| Molecular Weight(MW) | 26062 Da |
| Function | Transcriptional repressor. MXI1 binds with MAX to form a sequence-specific DNA-binding protein complex which recognizes the core sequence 5'-CAC[GA]TG-3'. MXI1 thus antagonizes MYC transcriptional activity by competing for MAX |
| Tissue Specificity | High levels found in the brain, heart and lung while lower levels are seen in the liver, kidney and skeletal muscle |
| Cellular Localization | Nucleus. |
| Entrez Gene | 4601 |
|---|---|
| Nucleotide Accession | NP_005953.4 NP_569157.2 NP_001008541.1 |
Application
MXI1 Antibody (Center) western blot analysis in mouse heart tissue lysates (35ug/lane).This demonstrates the MXI1 antibody detected the MXI1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
