Application
MYCPP Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MYCPP antibody detected the MYCPP protein (arrow).| Product Name | MYCPP Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | DENND4A; IRLB; MYCPBP; C-myc promoter-binding protein; DENN domain-containing protein 4A |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | IRLB MYCPBP |
|---|---|
| Alternative Names | DENND4A IRLB MYCPBP C-myc promoter-binding protein DENN domain-containing protein 4A |
| Molecular Weight(MW) | 209244 Da |
| Function | Probable guanine nucleotide exchange factor (GEF) which may activate RAB10. Promotes the exchange of GDP to GTP, converting inactive GDP-bound Rab proteins into their active GTP- bound form. According to PubMed:8056341, it may bind to ISRE-like element (interferon-stimulated response element) of MYC P2 promoter |
| Tissue Specificity | Expressed ubiquitously. Highest expression in bone marrow, medium in peripheral blood lymphocytes and lowest in spleen. In brain, breast, and prostate, higher expression was seen in normal cells than in tumor cells. Expression is regulated in a growth- and cell cycle-dependent manner |
| Cellular Localization | Nucleus (Probable). |
| Entrez Gene | 10260 |
|---|---|
| Nucleotide Accession | NP_005839.3 |
Application
MYCPP Antibody (C-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the MYCPP antibody detected the MYCPP protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
