Application
MYO1E Antibody (N-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the MYO1E antibody detected the MYO1E protein (arrow).| Product Name | MYO1E Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MYO1E; MYO1C; Unconventional myosin-Ie; Myosin-Ic; Unconventional myosin 1E |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MYO1C |
|---|---|
| Alternative Names | MYO1E MYO1C Unconventional myosin-Ie Myosin-Ic Unconventional myosin 1E |
| Molecular Weight(MW) | 127062 Da |
| Function | Myosins are actin-based motor molecules with ATPase activity. Unconventional myosins serve in intracellular movements Their highly divergent tails bind to membranous compartments, which are then moved relative to actin filaments. Binds to membranes containing anionic phospholipids via its tail domain Required for normal morphology of the glomerular basement membrane, normal development of foot processes by kidney podocytes and normal kidney function. In dendritic cells, may control the movement of class II-containing cytoplasmic vesicles along the actin cytoskeleton by connecting them with the actin network via ARL14EP and ARL14 |
| Tissue Specificity | Expressed in the immune system. In the kidney, predominantly expressed in the glomerulus, including podocytes |
| Cellular Localization | Cytoplasm. Cytoplasm, cytoskeleton. Cytoplasmic vesicle. Cytoplasmic vesicle, clathrin-coated vesicle Cell junction (By similarity). Note=Colocalizes with F-actin (By similarity). In cultured podocytes, it localizes close to and is associated with the cytoplasmic membrane, with enrichment at the lamellipodia tips. Colocalizes with cytoplasmic vesicles, including endocytic clathrin-coated vesicles. Colocalizes with dynamin at cytoplasmic vesicles |
| Entrez Gene | 4643 |
|---|---|
| Nucleotide Accession | NP_004989.2 |
Application
MYO1E Antibody (N-term) western blot analysis in T47D cell line lysates (35ug/lane).This demonstrates the MYO1E antibody detected the MYO1E protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
