MYRIP Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the MYRIP antibody detected the MYRIP protein (arrow).
MYRIP; SLAC2C; Rab effector MyRIP; Exophilin-8; Myosin-VIIa- and Rab-interacting protein; Synaptotagmin-like protein lacking C2 domains C
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
SLAC2C
Alternative Names
MYRIP SLAC2C Rab effector MyRIP Exophilin-8 Myosin-VIIa- and Rab-interacting protein Synaptotagmin-like protein lacking C2 domains C
Molecular Weight(MW)
95706 Da
Function
Rab effector protein involved in melanosome transport. Serves as link between melanosome-bound RAB27A and the motor proteins MYO5A and MYO7A. May link RAB27A-containing vesicles to actin filaments. Functions as a protein kinase A-anchoring protein (AKAP). May act as a scaffolding protein that links PKA to components of the exocytosis machinery, thus facilitating exocytosis, including insulin release (By similarity)
Tissue Specificity
Detected in brain, skin, heart, adrenal medulla, pancreas, intestine, liver, kidney, muscle and testis
Cellular Localization
Cytoplasm (By similarity). Cytoplasm, perinuclear region (By similarity). Cytoplasmic vesicle, secretory vesicle (By similarity). Note=In presynaptic and postsynaptic areas in photoreceptor cells and in the basal microvilli of retinal pigment epithelium cells. Associated with melanosomes Colocalizes with actin filaments (By similarity)
MYRIP Antibody (C-term) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the MYRIP antibody detected the MYRIP protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.