Application
Western blot analysis of MYOZ1 Antibody (Center) in MDA-MB231 cell line lysates (35ug/lane).MYOZ1 (arrow) was detected using the purified Pab.Application
MYOZ1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MYOZ1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.Application
MYOZ1 Antibody (Center) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Product Name | MYOZ1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | MYOZ1; MYOZ; Myozenin-1; Calsarcin-2; Filamin-, actinin- and telethonin-binding protein; Protein FATZ |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHCFC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MYOZ |
|---|---|
| Alternative Names | MYOZ1 MYOZ Myozenin-1 Calsarcin-2 Filamin- actinin- and telethonin-binding protein Protein FATZ |
| Molecular Weight(MW) | 31745 Da |
| Function | Myozenins may serve as intracellular binding proteins involved in linking Z-disk proteins such as alpha-actinin, gamma- filamin, TCAP/telethonin, LDB3/ZASP and localizing calcineurin signaling to the sarcomere. Plays an important role in the modulation of calcineurin signaling. May play a role in myofibrillogenesis |
| Tissue Specificity | Expressed primarily in skeletal muscle. Detected at lower levels in heart, prostate and pancreas |
| Cellular Localization | Nucleus. Cell projection, pseudopodium. Note=Localized to the nucleus and pseudopodia of undifferentiated cells and detected throughout the myotubes of differentiated cells. Colocalizes with ACTN2, FLNC and MYOT at the Z-lines of skeletal muscle |
| Entrez Gene | 58529 |
|---|
Application
Western blot analysis of MYOZ1 Antibody (Center) in MDA-MB231 cell line lysates (35ug/lane).MYOZ1 (arrow) was detected using the purified Pab.
Application
MYOZ1 Antibody (Center) immunohistochemistry analysis in formalin fixed and paraffin embedded mouse heart tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the MYOZ1 Antibody (Center) for immunohistochemistry. Clinical relevance has not been evaluated.
Application
MYOZ1 Antibody (Center) flow cytometric analysis of MDA-MB231 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
