Application
A. Western blot analysis on 293 cell lysate using anti-MYPT1 RabMAb (Cat. #AJ1523a).| Product Name | MYPT1 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | PPP1R12A, MBS, MYPT1, Protein phosphatase 1 regulatory subunit 12A, Myosin phosphatase-targeting subunit 1;Myosin phosphatase target subunit 1;Protein phosphatase myosin-binding subunit |
| Clonality | Monoclonal |
|---|---|
| Clone Number | Y110 |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:1000~10000 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | MBS MYPT1 |
|---|---|
| Alternative Names | PPP1R12A MBS MYPT1 Protein phosphatase 1 regulatory subunit 12A Myosin phosphatase-targeting subunit 1 Myosin phosphatase target subunit 1 Protein phosphatase myosin-binding subunit |
| Molecular Weight(MW) | 115281 Da |
| Function | Key regulator of protein phosphatase 1C (PPP1C). Mediates binding to myosin. As part of the PPP1C complex, involved in dephosphorylation of PLK1. Capable of inhibiting HIF1AN- dependent suppression of HIF1A activity |
| Tissue Specificity | Expressed in striated muscles, specifically in type 2a fibers (at protein level) |
| Cellular Localization | Cytoplasm. Note=Along actomyosin filaments and stress fibers |
| Entrez Gene | 4659 |
|---|
Application
A. Western blot analysis on 293 cell lysate using anti-MYPT1 RabMAb (Cat. #AJ1523a).| Application Notes | WB:1:1000~10000 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | 50 mM Tris-Glycine (pH 7.4), 0.15 M NaCl, 40% Glycerol, 0.01% sodium azide and 0.05% BSA. |
