N6AMT1 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the N6AMT1 antibody detected the N6AMT1 protein (arrow).
N6AMT1; C21orf127; HEMK2; HemK methyltransferase family member 2; M.HsaHemK2P; N(6)-adenine-specific DNA methyltransferase 1
Key Feature
Clonality
Polyclonal
Isotype
Ig
Host Species
Rabbit
Tested Applications
WB
WB:1:100~500
Species Reactivity
Human
Concentration
1mg/ml
Target Information
Gene Synonyms
C21orf127 HEMK2
Alternative Names
N6AMT1 C21orf127 HEMK2 HemK methyltransferase family member 2 M.HsaHemK2P N(6)-adenine-specific DNA methyltransferase 1
Molecular Weight(MW)
22900 Da
Function
Heterodimeric methyltransferase that catalyzes N5- methylation of ETF1 on 'Gln-185', using S-adenosyl L-methionine as methyl donor. ETF1 needs to be complexed to ERF3 in its GTP-bound form to be efficiently methylated. May play a role in the modulation of arsenic-induced toxicity. May be involved in the conversion of monomethylarsonous acid (3+) into the less toxic dimethylarsonic acid
Tissue Specificity
Widely expressed, with highest expression in parathyroid and pituitary glands, followed by adrenal gland and kidney, and lowest expression in leukocytes and mammary gland
N6AMT1 Antibody (N-term) western blot analysis in 293 cell line lysates (35ug/lane).This demonstrates the N6AMT1 antibody detected the N6AMT1 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.