Application
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Natriuretic Peptide Receptor A (NPR1/ANPA) antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | Natriuretic Peptide Receptor A Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NPR1; ANPRA; Atrial natriuretic peptide receptor 1; Atrial natriuretic peptide receptor type A; Guanylate cyclase A |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | IHC |
| IHC:1:10~50 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ANPRA |
|---|---|
| Alternative Names | NPR1 ANPRA Atrial natriuretic peptide receptor 1 Atrial natriuretic peptide receptor type A Guanylate cyclase A |
| Molecular Weight(MW) | 118919 Da |
| Function | Receptor for the atrial natriuretic peptide NPPA/ANP and the brain natriuretic peptide NPPB/BNP which are potent vasoactive hormones playing a key role in cardiovascular homeostasis. Has guanylate cyclase activity upon binding of the ligand |
| Tissue Specificity | This Natriuretic Peptide Receptor A Antibody antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 1~30 amino acids from the N-terminal region of human ANPA. |
| Cellular Localization | Membrane; Single-pass type I membrane protein |
| Entrez Gene | 4881 |
|---|
Application
Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with Natriuretic Peptide Receptor A (NPR1/ANPA) antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | IHC:1:10~50 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein G column, eluted with high and low pH buffers and neutralized immediately, followed by dialysis against PBS. |
