Application
NCAPH Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the NCAPH antibody detected the NCAPH protein (arrow).| Product Name | NCAPH Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NCAPH; BRRN; BRRN1; CAPH; KIAA0074; Condensin complex subunit 2; Barren homolog protein 1; Chromosome-associated protein H; Non-SMC condensin I complex subunit H; XCAP-H homolog |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BRRN BRRN1 CAPH KIAA0074 |
|---|---|
| Alternative Names | NCAPH BRRN BRRN1 CAPH KIAA0074 Condensin complex subunit 2 Barren homolog protein 1 Chromosome-associated protein H Non-SMC condensin I complex subunit H XCAP-H homolog |
| Molecular Weight(MW) | 82563 Da |
| Function | Regulatory subunit of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases |
| Tissue Specificity | Widely expressed at low level. Expressed in proliferating cells |
| Cellular Localization | Nucleus. Cytoplasm. Chromosome. Note=In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDK1, leading to condensin's association with chromosome arms and to chromosome condensation Dissociation from chromosomes is observed in late telophase |
| Entrez Gene | 23397 |
|---|---|
| Nucleotide Accession | NP_056156.2 |
Application
NCAPH Antibody (Center) western blot analysis in K562 cell line lysates (35ug/lane).This demonstrates the NCAPH antibody detected the NCAPH protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
