Application
NCDN Antibody (N-term) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the NCDN antibody detected the NCDN protein (arrow).| Product Name | NCDN Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NCDN; KIAA0607; Neurochondrin |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA0607 |
|---|---|
| Alternative Names | NCDN KIAA0607 Neurochondrin |
| Molecular Weight(MW) | 78864 Da |
| Function | Probably involved in signal transduction, in the nervous system, via increasing cell surface localization of GRM5 and positively regulating its signaling (By similarity). Required for the spatial learning process. Acts as a negative regulator of Ca(2+)-calmodulin-dependent protein kinase 2 (CaMK2) phosphorylation. May play a role in modulating melanin- concentrating hormone-mediated functions via its interaction with MCHR1 that interferes with G protein-coupled signal transduction May be involved in bone metabolism. May also be involved in neurite outgrowth |
| Tissue Specificity | Abundantly expressed in whole adult brain and in all individual brain regions examined, including spinal cord Weakly expressed in ovary, testis, fetal brain and small intestine |
| Cellular Localization | Cytoplasm, cytosol. Cell projection, dendrite. Note=Localizes to somatic regions of neurons |
| Entrez Gene | 23154 |
|---|---|
| Nucleotide Accession | NP_001014841.1 NP_055099.1 |
Application
NCDN Antibody (N-term) western blot analysis in Y79 cell line lysates (35ug/lane).This demonstrates the NCDN antibody detected the NCDN protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
