Application
NCKAP1 Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the NCKAP1 antibody detected the NCKAP1 protein (arrow).| Product Name | NCKAP1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NCKAP1; HEM2; KIAA0587; NAP1; Nck-associated protein 1; Membrane-associated protein HEM-2; p125Nap1 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HEM2 KIAA0587 NAP1 |
|---|---|
| Alternative Names | NCKAP1 HEM2 KIAA0587 NAP1 Nck-associated protein 1 Membrane-associated protein HEM-2 p125Nap1 |
| Molecular Weight(MW) | 128790 Da |
| Function | Part of the WAVE complex that regulates lamellipodia formation. The WAVE complex regulates actin filament reorganization via its interaction with the Arp2/3 complex. Actin remodeling activity is regulated by RAC1 |
| Tissue Specificity | Expressed in all tissues examined except peripheral blood leukocytes, with highest expression in brain, heart, and skeletal muscle |
| Cellular Localization | Cell membrane; Single-pass membrane protein; Cytoplasmic side (By similarity). Cell projection, lamellipodium membrane; Single-pass membrane protein; Cytoplasmic side (By similarity). Note=At the interface between the lamellipodial actin meshwork and the membrane (By similarity) |
| Entrez Gene | 10787 |
|---|---|
| Nucleotide Accession | NP_038464.1 NP_995314.1 |
Application
NCKAP1 Antibody (Center) western blot analysis in A2058 cell line lysates (35ug/lane).This demonstrates the NCKAP1 antibody detected the NCKAP1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
