Application
Western blot analysis of NCR3 Antibody (Center) in MDA-MB435 cell line lysates (35ug/lane). NCR3 (arrow) was detected using the purified Pab.| Product Name | NCR3 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NCR3; 1C7; LY117; Natural cytotoxicity triggering receptor 3; Activating natural killer receptor p30; Natural killer cell p30-related protein; CD_antigen=CD337; Flags: Precursor |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | 1C7 LY117 |
|---|---|
| Alternative Names | NCR3 1C7 LY117 Natural cytotoxicity triggering receptor 3 Activating natural killer receptor p30 Natural killer cell p30-related protein CD_antigen=CD337 Flags: Precursor |
| Molecular Weight(MW) | 21593 Da |
| Function | Cytotoxicity-activating receptor that contributes to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. Engagement of NCR3 by BAG6 also promotes dendritic cell (DC) maturation, both through killing those DCs that did not properly acquire a mature phenotype, and inducing NK cells to release TNFA and IFNG, which promotes DC maturation |
| Tissue Specificity | Selectively expressed by all resting and activated NK cells and weakly expressed in spleen |
| Cellular Localization | Cell membrane; Single-pass type I membrane protein |
| Entrez Gene | 259197 |
|---|
Application
Western blot analysis of NCR3 Antibody (Center) in MDA-MB435 cell line lysates (35ug/lane). NCR3 (arrow) was detected using the purified Pab.| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
