Application
NDST3 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the NDST3 antibody detected the NDST3 protein (arrow).| Product Name | NDST3 Antibody (C-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NDST3; HSST3; Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3; Glucosaminyl N-deacetylase/N-sulfotransferase 3; N-heparan sulfate sulfotransferase 3; Heparan sulfate N-deacetylase 3; Heparan sulfate N-sulfotransferase 3 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | HSST3 |
|---|---|
| Alternative Names | NDST3 HSST3 Bifunctional heparan sulfate N-deacetylase/N-sulfotransferase 3 Glucosaminyl N-deacetylase/N-sulfotransferase 3 N-heparan sulfate sulfotransferase 3 Heparan sulfate N-deacetylase 3 Heparan sulfate N-sulfotransferase 3 |
| Molecular Weight(MW) | 100902 Da |
| Function | Essential bifunctional enzyme that catalyzes both the N- deacetylation and the N-sulfation of glucosamine (GlcNAc) of the glycosaminoglycan in heparan sulfate. Modifies the GlcNAc-GlcA disaccharide repeating sugar backbone to make N-sulfated heparosan, a prerequisite substrate for later modifications in heparin biosynthesis. Has high deacetylase activity but low sulfotransferase activity |
| Tissue Specificity | Expressed in brain, kidney, liver, fetal and adult lung, adult pancreas, placenta, fetal spleen and fetal thymus. Not detected in adult/ fetal heart and skeletal muscle |
| Cellular Localization | Golgi apparatus membrane; Single-pass type II membrane protein (By similarity) |
| Entrez Gene | 9348 |
|---|---|
| Nucleotide Accession | NP_004775.1 |
Application
NDST3 Antibody (C-term) western blot analysis in HL-60 cell line lysates (35ug/lane).This demonstrates the NDST3 antibody detected the NDST3 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
