Application
NDRG2 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the NDRG2 antibody detected the NDRG2 protein (arrow).| Product Name | NDRG2 Antibody (N-term) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NDRG2; KIAA1248; SYLD; Protein NDRG2; N-myc downstream-regulated gene 2 protein; Protein Syld709613 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | KIAA1248 SYLD |
|---|---|
| Alternative Names | NDRG2 KIAA1248 SYLD Protein NDRG2 N-myc downstream-regulated gene 2 protein Protein Syld709613 |
| Molecular Weight(MW) | 40798 Da |
| Function | Contributes to the regulation of the Wnt signaling pathway. Down-regulates CTNNB1-mediated transcriptional activation of target genes, such as CCND1, and may thereby act as tumor suppressor. May be involved in dendritic cell and neuron differentiation |
| Tissue Specificity | Highly expressed in brain, heart, skeletal muscle and salivary gland, and moderately in kidney and liver Expressed in dendritic cells, but not in other blood cells Expression levels are low in pancreatic and liver cancer tissues; absent in meningioma. Expressed in low-grade gliomas but present at low levels in glioblastoma. Isoform 1 and isoform 2 are present in brain neurons and up-regulated in Alzheimer disease (at protein level) |
| Cellular Localization | Cytoplasm. Cytoplasm, perinuclear region. Cell projection, growth cone (By similarity). Note=In neurons, seems to concentrate at axonal growth cone. Perinuclear in neurons (By similarity) |
| Entrez Gene | 57447 |
|---|---|
| Nucleotide Accession | NP_963833.1 NP_963831.1 NP_963834.1 |
Application
NDRG2 Antibody (N-term) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the NDRG2 antibody detected the NDRG2 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
