Application
NDRG4 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the NDRG4 antibody detected the NDRG4 protein (arrow).| Product Name | NDRG4 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NDRG4; BDM1; KIAA1180; Protein NDRG4; Brain development-related molecule 1; N-myc downstream-regulated gene 4 protein; Vascular smooth muscle cell-associated protein 8 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | BDM1 KIAA1180 |
|---|---|
| Alternative Names | NDRG4 BDM1 KIAA1180 Protein NDRG4 Brain development-related molecule 1 N-myc downstream-regulated gene 4 protein Vascular smooth muscle cell-associated protein 8 |
| Molecular Weight(MW) | 38459 Da |
| Function | Contributes to the maintenance of intracerebral BDNF levels within the normal range, which is necessary for the preservation of spatial learning and the resistance to neuronal cell death caused by ischemic stress (By similarity). May enhance growth factor-induced ERK1 and ERK2 phosphorylation, including that induced by PDGF and FGF. May attenuate NGF-promoted ELK1 phosphorylation in a microtubule-dependent manner |
| Tissue Specificity | Expressed predominantly in brain and heart (at protein level). In the brain, detected in astrocytes. Isoform 1 and isoform 2 are only expressed in brain. Isoform 3 is expressed in both heart and brain. Up-regulated in glioblastoma multiforme cells |
| Cellular Localization | Cytoplasm, cytosol. |
| Entrez Gene | 65009 |
|---|---|
| Nucleotide Accession | NP_001123959.1 NP_065198.1 |
Application
NDRG4 Antibody (Center) western blot analysis in CEM cell line lysates (35ug/lane).This demonstrates the NDRG4 antibody detected the NDRG4 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
