Application
NET1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the NET1 antibody detected the NET1 protein (arrow).Application
NET1 Antibody (Center) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the NET1 antibody detected the NET1 protein (arrow).| Product Name | NET1 Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NET1; ARHGEF8; Neuroepithelial cell-transforming gene 1 protein; Proto-oncogene p65 Net1; Rho guanine nucleotide exchange factor 8 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WB |
| WB:1:100~500 |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | ARHGEF8 |
|---|---|
| Alternative Names | NET1 ARHGEF8 Neuroepithelial cell-transforming gene 1 protein Proto-oncogene p65 Net1 Rho guanine nucleotide exchange factor 8 |
| Molecular Weight(MW) | 67740 Da |
| Function | Acts as guanine nucleotide exchange factor (GEF) for RhoA GTPase. May be involved in activation of the SAPK/JNK pathway Stimulates genotoxic stress-induced RHOB activity in breast cancer cells leading to their cell death |
| Tissue Specificity | Widely expressed. |
| Cellular Localization | Cytoplasm (By similarity). Nucleus (By similarity) |
| Entrez Gene | 10276 |
|---|---|
| Nucleotide Accession | NP_001040625.1 NP_005854.2 |
Application
NET1 Antibody (Center) western blot analysis in Hela cell line lysates (35ug/lane).This demonstrates the NET1 antibody detected the NET1 protein (arrow).
Application
NET1 Antibody (Center) western blot analysis in mouse lung tissue lysates (35ug/lane).This demonstrates the NET1 antibody detected the NET1 protein (arrow).| Application Notes | WB:1:100~500 |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
Data sheet for OM215210