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NETO2 Antibody (N-term )

Catalog Number:OM215212
OM215212
Discount Price
OM215212-100ul
1~2 Week
100ul
OM215212-50ul
50ul
OM215212-20ul
20ul
1~2 Week
Product Profile
Product Name NETO2 Antibody (N-term )
Antibody Type Primary Antibodies
Antigen Alias NETO2; BTCL2; Neuropilin and tolloid-like protein 2; Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms BTCL2
Alternative Names NETO2
BTCL2
Neuropilin and tolloid-like protein 2
Brain-specific transmembrane protein containing 2 CUB and 1 LDL-receptor class A domains protein 2
Molecular Weight(MW) 59393 Da
Function Accessory subunit of neuronal kainate-sensitive glutamate receptors, GRIK2 and GRIK3. Increases kainate-receptor channel activity, slowing the decay kinetics of the receptors, without affecting their expression at the cell surface, and increasing the open probability of the receptor channels Modulates the agonist sensitivity of kainate receptors. Slows the decay of kainate receptor-mediated excitatory postsynaptic currents (EPSCs), thus directly influencing synaptic transmission (By similarity)
Tissue Specificity This NETO2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 173-203 amino acids from the N-terminal region of human NETO2.
Cellular Localization Membrane; Single-pass type I membrane protein (Potential)
Database Links
Entrez Gene 81831
Nucleotide Accession NP_060562.3
Application

Application

NETO2 Antibody (N-term ) western blot analysis in Jurkat cell line lysates (35ug/lane).This demonstrates the NETO2 antibody detected the NETO2 protein (arrow).

Application

NETO2 Antibody (N-term ) immunohistochemistry analysis in formalin fixed and paraffin embedded human colon carcinoma followed by peroxidase conjugation of the secondary antibody and DAB staining.This data demonstrates the use of NETO2 Antibody (N-term ) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

NETO2 Antibody (N-term ) flow cytometric analysis of Jurkat cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated donkey-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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