NEU1 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the NEU1 antibody detected the NEU1 protein (arrow).
Catalyzes the removal of sialic acid (N-acetylneuramic acid) moities from glycoproteins and glycolipids. To be active, it is strictly dependent on its presence in the multienzyme complex Appears to have a preference for alpha 2-3 and alpha 2-6 sialyl linkage
Tissue Specificity
Highly expressed in pancreas, followed by skeletal muscle, kidney, placenta, heart, lung and liver. Weakly expressed in brain
Cellular Localization
Lysosome membrane; Peripheral membrane protein; Lumenal side. Lysosome lumen. Cell membrane. Cytoplasmic vesicle. Note=Localized not only on the inner side of the lysosomal membrane and in the lysosomal lumen, but also on the plasma membrane and in intracellular vesicles
NEU1 Antibody (Center) western blot analysis in HepG2 cell line lysates (35ug/lane).This demonstrates the NEU1 antibody detected the NEU1 protein (arrow).
Application Notes
WB:1:100~500
Additional Information
Form
Liquid
Storage Instructions
For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer
Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.