Application
Western blot analysis of NEURL Antibody (Center) in Y79 cell line lysates (35ug/lane). NEURL (arrow) was detected using the purified Pab.Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with NEURL Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Product Name | NEURL Antibody (Center) |
|---|---|
| Antibody Type | Primary Antibodies |
| Antigen Alias | NEURL; NEURL1; NEURL1A; RNF67; Neuralized-like protein 1A; RING finger protein 67 |
| Clonality | Polyclonal |
|---|---|
| Isotype | Ig |
| Host Species | Rabbit |
| Tested Applications | WBIHC |
| WB:1:100~500 IHC |
|
| Species Reactivity | Human |
| Concentration | 1mg/ml |
| Gene Synonyms | NEURL1 NEURL1A RNF67 |
|---|---|
| Alternative Names | NEURL NEURL1 NEURL1A RNF67 Neuralized-like protein 1A RING finger protein 67 |
| Molecular Weight(MW) | 61860 Da |
| Function | May function as an E3 ubiquitin-protein ligase to activate monoubiquitination of JAG1, thereby regulating the Notch pathway (By similarity) |
| Tissue Specificity | Expressed in brain, testis, pituitary gland, pancreas and bone marrow. Also poorly expressed in an malignant astrocytomas and several neuroectodermal tumor cell lines |
| Cellular Localization | Cell membrane; Peripheral membrane protein (By similarity). Cytoplasm, perinuclear region |
| Entrez Gene | 9148 |
|---|
Application
Western blot analysis of NEURL Antibody (Center) in Y79 cell line lysates (35ug/lane). NEURL (arrow) was detected using the purified Pab.
Application
Formalin-fixed and paraffin-embedded human brain tissue reacted with NEURL Antibody (Center), which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.| Application Notes | WB:1:100~500 IHC |
|---|
| Form | Liquid |
|---|---|
| Storage Instructions | For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles. |
| Storage Buffer | Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification. |
