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NEURL1B Antibody (N-term)

Catalog Number:OM215221
OM215221
Discount Price
OM215221-100ul
1~2 Week
100ul
OM215221-50ul
50ul
OM215221-20ul
20ul
1~2 Week
Product Profile
Product Name NEURL1B Antibody (N-term)
Antibody Type Primary Antibodies
Antigen Alias NEURL1B; NEURL3; E3 ubiquitin-protein ligase NEURL1B; Neuralized-like protein 1B; Neuralized-like protein 3
Key Feature
Clonality Polyclonal
Isotype Ig
Host Species Rabbit
Tested Applications WBIHCFC
WB:1:100~500 IHC
Species Reactivity Human
Concentration 1mg/ml
Target Information
Gene Synonyms NEURL3
Alternative Names NEURL1B
NEURL3
E3 ubiquitin-protein ligase NEURL1B
Neuralized-like protein 1B
Neuralized-like protein 3
Molecular Weight(MW) 59270 Da
Function E3 ubiquitin-protein ligase involved in regulation of the Notch pathway through influencing the stability and activity of several Notch ligands
Tissue Specificity Highest expression in brain, prostate and small intestine. In the brain the levels are higher in fetal than in adult stage. In the adult brain the highest levels are detected in the olfactory system, cerebellar cortex, optic nerve and the frontal lobe
Cellular Localization Cytoplasm.
Database Links
Entrez Gene 54492
Nucleotide Accession NP_001136123.1
Application

Application

NEURL1B Antibody (N-term) western blot analysis in Neuro-2a cell line lysates (35ug/lane).This demonstrates the NEURL1B antibody detected the NEURL1B protein (arrow).

Application

NEURL1B Antibody (N-term) immunohistochemistry analysis in formalin fixed and paraffin embedded human brain tissue followed by peroxidase conjugation of the secondary antibody and DAB staining. This data demonstrates the use of the NEURL1B Antibody (N-term) for immunohistochemistry. Clinical relevance has not been evaluated.

Application

NEURL1B Antibody (N-term) flow cytometric analysis of 293 cells (right histogram) compared to a negative control cell (left histogram).FITC-conjugated goat-anti-rabbit secondary antibodies were used for the analysis.
Application Notes WB:1:100~500 IHC
Additional Information
Form Liquid
Storage Instructions For short-term storage, store at 4° C. For long-term storage, aliquot and store at -20ºC or below. Avoid multiple freeze-thaw cycles.
Storage Buffer Purified polyclonal antibody supplied in PBS with 0.09% (W/V) sodium azide. This antibody is purified through a protein A column, followed by peptide affinity purification.
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